The blaze happened at around 1.15am in Low Hill, Wolverhampton, and when emergency services rushed to the scene, they rescued the man from the building. Despite the best efforts of medics, he was pronounced dead at the scene.
Neighbours told of their shock as police continue to investigate the fire.
One man said: “It is such a shock. My mum said that she saw police cars but I didn’t imagine this.
“There’s always something happening around here.”
Forensic officers are present on the housing estate, reports Birmingham Live.
A spokesman for West Midlands Ambulance Service said: “On arrival crews discovered one patient, a man, who had been rescued from the property by the fire service.
Sadly, it quickly became apparent nothing could be done to save him and he was confirmed dead at the scene.”
The entire property has been taped off by the fire service as the morning has progressed, with an investigation likely to continue into Thursday afternoon (December 30).
While police officers currently remain at the scene alongside firefighters, they currently don’t believe the fire to be caused by arson.
A spokesman for West Midlands Police said: “The fire is not currently being treated as suspicious.”
The Low Hill estate is to the north east of Wolverhampton city centre and houses around 3,000 people in total.