That averages out at a massive 63 per day and 2.6 per hour.
The next highest came on the A282 Dartford Tunnel Approach Road in Kent, which saw 52,548 activations.
A slight step down from the number one, this was at an average of 44 flashes per day and 1.8 per hour.
Third place went to a camera at the A1081 Airport Way in Luton, Bedfordshire, with 43,783 activations at an average of 36 per day and 1.5 per hour.
Surrey had a second camera in the top five with the M3 Junction 2-4 in fourth at 40,150, while Sussex had their highest single camera at fifth on the A270 Lewes Road in Brighton, at 35,897 total activations.